PubChem lets users search chemical information by name, molecular formula, structure and other identifiers.
The Best ChemSpider Alternatives in 2026
Looking for something like ChemSpider? Here are 17 alternatives, ranked by how closely they match it on purpose, features and platforms. Of these, 1 are free or have a free plan.
Search chemical structures and text records in ChemSpider, a database of more than 130 million compounds.
Top picks at a glance
Quick comparison
| # | Alternative | Pricing | Open source | Platforms |
|---|---|---|---|---|
| 1 | PubChem | — | Not stated | Web |
| 2 | Wolfram Alpha Chemistry | — | Not stated | Web |
| 3 | ChemTube3D | — | Not stated | Web |
| 4 | NIST | — | Not stated | Web |
| 5 | Arkivoc | — | Not stated | Web |
| 6 | ChemistrySteps | — | Not stated | Web |
| 7 | Organic Chemistry | — | Not stated | Web |
| 8 | name-reaction | — | Not stated | Web |
| 9 | Organic Chemistry Data | — | Not stated | Web |
| 10 | CommonOrganicChemistry | — | Not stated | Web |
All ChemSpider alternatives
Wolfram Alpha Chemistry
wolframalpha.com/examples/science-and-technolo…Chemistry examples from Wolfram Alpha cover data and computations for compounds, reactions, thermodynamics, quantum chemistry, and more.
ChemTube3D
chemtube3d.comChemTube3D teaches chemistry through interactive 3D animations of molecular structures and reactions.
NIST
webbook.nist.gov/chemistryThe NIST Chemistry WebBook provides online property data for chemical species.
Arkivoc
arkat-usa.orgARKIVOC provides chemistry journal content, with browsing and search for articles and conference material.
ChemistrySteps
chemistrysteps.comChemistry Steps provides organic chemistry study materials, practice problems, summary sheets and multiple-choice quizzes.
Organic Chemistry
organic-chemistry.orgThe Organic Chemistry Portal summarizes recent literature and resources about organic chemistry reactions.
name-reaction
name-reaction.comName-Reaction.com provides information about organic chemistry name reactions and their mechanisms.
Organic Chemistry Data
organicchemistrydata.orgOrganic Chemistry Data collects chemistry information, reference data, and resources and currently displays a site upgrade notice.
CommonOrganicChemistry
commonorganicchemistry.comCommonOrganicChemistry provides mechanisms, procedures and details for commonly encountered organic chemistry reactions.
LibreTexts Chemistry
chem.libretexts.orgThe LibreTexts Chemistry library presents online instructional material organized into topics and sections.
PeriodicVideos
periodicvideos.comPeriodicVideos shares short videos about each element in the periodic table and links to related science video channels.
chemguide
chemguide.co.ukChemguide explains chemistry concepts for students in upper-level courses.
ChemQuiz helps high school and introductory college students practice chemistry skills.
Science Geek
sciencegeek.netScienceGeek.net supports high-school science study in chemistry, AP Chemistry and biology.
Zperiod
zperiod.appZperiod is an educational web application with an interactive periodic table covering 118 elements, 3D atom models, ions, chemistry tools, and worksheet practice.
Compound Interest
compoundchem.com/infographicsCompound Interest explains everyday chemical compounds through topic pages on chemistry and related fields.
Alternatives to similar tools
What is the best alternative to ChemSpider?
Is there a free alternative to ChemSpider?
Alternatives are suggested from the purpose and features described in our listings. Different pages for the same product appear once. Read each description to check whether it fits your task. How we choose alternatives · Suggest an alternative












