The Demographic and Health Surveys Program provides information to support population, health, and nutrition programs.
Dataset
Allele Frequency Net Database
The Allele Frequency Net Database catalogs allele, haplotype and genotype frequencies across populations.
About Allele Frequency Net Database
The Allele Frequency Net Database is a freely available repository of immune gene frequencies in worldwide populations, covering HLA, KIR, cytokine and MIC data in allele, haplotype and genotype formats. Users can search existing data by population and gene system, including HLA allele, haplotype and rare-allele searches and KIR gene and genotype searches, with a low-resolution option when high-resolution data is unavailable, and can submit frequency or raw genotype data.
HLA datasets are classified into Gold-Silver-Bronze quality standards, and continued growth depends on users contributing data.
Key features
- Search HLA allele frequencies across worldwide populations
- Search HLA haplotype frequencies
- Search HLA rare alleles
- Search KIR gene and genotype data
- Use low-resolution search when high-resolution data is missing
- Submit HLA frequency, non-HLA frequency, and raw genotype data
Best for: Researchers and clinicians using population frequencies of HLA, KIR, and other immune genes.
Good for
- Freely available repository for immune gene frequencies
- Stores allele, haplotype and genotype data for HLA, KIR, cytokine and MIC
- Labels HLA datasets with Gold-Silver-Bronze quality standards
Watch out for
- High-resolution allele data is not available in all cases
- Dataset quality varies across Gold, Silver and Bronze classifications
- Continued growth depends on users contributing data
Allele Frequency Net Database at a glance
- Official website
- allelefrequencies.net
- Category
- Research & Data › Health & Medical Data
- Type
- Dataset
- Platforms
- Web
- Last checked
- Oct 5, 2026 · Online when checked
- Listed
- Oct 5, 2026
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Allele Frequency Net Database FAQ
How good are the datasets in AFND?
HLA datasets are classified into Gold-Silver-Bronze standards.
How should I cite AFND?
Cite the 2020 update publication by Gonzalez-Galarza et al. in Nucleic Acids Research 2020, 48, D783-8, and also cite the original publication for the data.
Can I contribute population frequency data?
Yes. Users can add HLA frequency data, non-HLA frequency data, and HLA genotype raw data for SPR to the common database.
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