DISGENET provides curated gene-disease and variant-disease associations, with a REST API, R package, and Cytoscape app.
Leiden Open Variation Database
LOVD is an open-source system for displaying gene-centered DNA variants and finding locus-specific databases.
About Leiden Open Variation Database
Leiden Open Variation Database (LOVD) is a system for collecting, displaying and curating DNA variants, with gene-centered and patient-centered views. It helps users find locus-specific databases for a gene of interest and search for variants across public LOVD installations.
It connects with resources including HGNC, NCBI, EBI, VariantValidator and Mutalyzer, using VariantValidator and Mutalyzer for nomenclature checking during submission. The Leiden server provides hosting and support for LOVD-powered gene variant databases.
Key features
- Gene-centered collection and display of DNA variants
- Patient-centered and gene-centered views of data
- Search variants across public LOVD installations
- List of locus-specific databases by gene of interest
- Nomenclature checking via VariantValidator and Mutalyzer during submission
- Connects with HGNC, NCBI, EBI resources to support data quality
Best for: Researchers and database curators working with gene-associated DNA variants and phenotypes.
Good for
- Supports both patient-centered and gene-centered views
- Checks variant nomenclature during submission via VariantValidator and Mutalyzer
- Connects with HGNC, NCBI and EBI resources to support data quality
Leiden Open Variation Database at a glance
- Website
- lovd.nl/3.0/home
- Category
- Research & Data › Open Data & Datasets
- Type
- Website
- Pricing
- Not confirmed. Check the site
- Platforms
- Web
- Open source
- Not stated
- Last checked
- Oct 5, 2026 · Online when checked
- Listed
- Oct 5, 2026
Leiden Open Variation Database alternatives
Tools and sites you could use instead, ranked by how closely they match.
The Gene Ontology project represents knowledge about gene functions across molecular, cellular, and tissue system levels.
The Database of Zeolite Structures provides searchable structural information, descriptions, drawings, and animated displays for approved zeolite framework types.
Synapse supports scientific collaborations centered on shared biomedical datasets and research projects.
Search structural variants in autism spectrum disorder through the Autism Chromosome Rearrangement Database.
HGVD provides a searchable catalog of genetic variants and allele frequencies focused on the Japanese population.
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Leiden Open Variation Database FAQ
What does LOVD stand for?
Leiden Open (source) Variation Database.
How can I find databases for a specific gene?
Use the LSDB list to see all databases for a gene of interest, such as DMD.lovd.nl or BRCA1.lovd.nl.
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