Mouse Models of Human Cancer database

MMHCdb helps researchers compare mouse cancer models, tumor mutations, and genes associated with cancer types.

tumor.informatics.jax.org/mtbwi/index.do
Mouse Models of Human Cancer database homepage screenshot

About Mouse Models of Human Cancer database

The Mouse Models of Human Cancer Database (MMHCdb) helps researchers choose experimental models, review patterns of mutations in specific cancers, and identify genes commonly mutated across cancers.

It includes records on spontaneous and induced tumors in mice, genetically defined strains including inbred, hybrid, mutant and genetically engineered mice, and Patient Derived Xenograft (PDX) models, with Advanced Search, Tumor Frequency Grid, PDX search, and PDX STR Profiler.

Key features

  • Search spontaneous and induced tumors in mice
  • Browse genetically defined inbred, hybrid, mutant mouse strains
  • Search Patient Derived Xenograft (PDX) models
  • Compare tumor frequencies across cancer sites and strains
  • Use PDX STR Profiler under Searches / Tools
  • View mini-grids of tumor frequency by genetic background
Best for: Researchers choosing experimental mouse models and reviewing mutation patterns across cancers.
Good for
  • Contains over 110,000 tumor frequency records as of April 2022
  • Covers spontaneous, induced, genetically defined, and PDX models
  • Provides tutorial videos for Advanced Search and other search pages

Mouse Models of Human Cancer database at a glance

Type
Website
Pricing
Not confirmed. Check the site
Platforms
Web
Open source
Not stated
Last checked
Oct 5, 2026 · Online when checked
Listed
Oct 5, 2026

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Mouse Models of Human Cancer database FAQ

What types of mouse cancer models are included?
Spontaneous and induced tumors, genetically defined strains including inbred, hybrid, mutant and genetically engineered mice, and Patient Derived Xenograft models.
What search tools does MMHCdb provide?
Advanced Search, Tumor Frequency Grid, Patient Derived Xenograft search, and PDX STR Profiler under Searches / Tools.
Is help available for using the database?
Tutorial videos covering the Advanced Search Page, Tumor Frequency Grid, Patient Derived Xenograft Search Page, and a general overview are posted on its YouTube page.
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