The Drosophila Synthetic Population Resource provides a population resource for genetic analysis of complex traits.

wfitch.bio.uci.edu/~dspr/index.html
DSPR homepage screenshot

About DSPR

DSPR (Drosophila Synthetic Population Resource) is a community resource for genetic analysis of complex traits in Drosophila melanogaster. It provides over 1,700 recombinant inbred lines (RILs) from two highly recombined synthetic populations, each built from a different set of eight inbred founder lines, with one founder line common to both. Complete genome sequence data for the founder lines and high-resolution genetic maps for each RIL are available. The site documents the resource, its analytical machinery, and how to obtain RILs or genomic data, and is intended for use by the Drosophila research community.

Key features

  • Over 1,700 Drosophila melanogaster recombinant inbred lines (RILs) for QTL mapping
  • Two synthetic populations made from different sets of eight inbred founders
  • Complete genome sequence data for the founder lines
  • High-resolution genetic map for each RIL
  • Designed for mapping QTLs to 1-2 cM regions
  • Analytical machinery and information for requesting RILs or data
Best for: Drosophila researchers and geneticists studying the genetic basis of complex traits through high-resolution QTL mapping.
Good for
  • Provides a large panel of genotyped RILs with fully sequenced founder lines
  • Supports high mapping resolution to 1-2 cM regions containing a handful of genes
  • Allows estimation of both QTL effect and frequency from multi-founder RILs
Watch out for
  • Focused on Drosophila melanogaster and the Drosophila research community
  • Not open source

DSPR at a glance

Type
Website
Pricing
Not confirmed. Check the site
Platforms
Web
Open source
Not stated
Last checked
Oct 6, 2026 · Online when checked
Listed
Oct 5, 2026

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DSPR FAQ

What does the DSPR resource include?
It includes over 1,700 recombinant inbred lines of Drosophila melanogaster, complete genome sequence data for the founder lines, and a high-resolution genetic map for each RIL.
How can researchers obtain the RILs or genomic data?
The site provides information on how to obtain the RILs and/or genomic data, including pages for requesting flies and accessing data.
What mapping resolution does the DSPR support?
The design allows QTLs to be mapped to narrow regions of 1-2 cM, encompassing a handful of genes.
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