The Integrated Interactions Database lets users search interaction data by gene or protein identifiers and organism.
BioGRID
Search BioGRID's online repository of protein, chemical, and genetic interaction data.
About BioGRID
BioGRID is an online biomedical interaction repository with data compiled through curation. Its version 5.0.262 index searches 88,812 publications for 3,035,956 protein and genetic interactions, 31,540 chemical interactions, and 1,128,339 post-translational modifications from major model organism species. All data are freely provided through the search index and available for download in standardized formats. Related resources include BioGRID ORCS, a repository of curated genome-wide CRISPR screens updated quarterly, and themed curation projects focused on disease-relevant biological processes.
Key features
- Search curated protein and genetic interactions across major model organism species
- Search chemical interactions and post-translational modifications
- Download datasets in multiple standardized formats
- ORCS repository of curated genome-wide CRISPR screens, updated quarterly
- ORCS searchable by gene/protein, phenotype, cell line and authors
- Themed curation projects focused on disease-relevant biological processes
Best for: Researchers and scientists who need curated protein, genetic, chemical interaction, and CRISPR screen data.
Good for
- Data are freely provided through search and downloadable formats
- Covers protein, genetic, chemical interactions, and post-translational modifications
- ORCS includes structured metadata for curated CRISPR screens
Watch out for
- Interaction data cover major model organism species, not all organisms
- ORCS is updated quarterly, so its content follows that schedule
BioGRID at a glance
- Website
- thebiogrid.org
- Category
- Research & Data › Open Data & Datasets
- Type
- Website
- Pricing
- Not confirmed. Check the site
- Platforms
- Web
- Open source
- Not stated
- Language
- English
- Last checked
- Oct 6, 2026 · Online when checked
- Listed
- Oct 5, 2026
BioGRID alternatives
Tools and sites you could use instead, ranked by how closely they match.
TheCellMap provides interactive views of genetic interaction networks in budding yeast and human haploid cells.
VirHostNet integrates and curates virus-host protein interaction data for reproducible systems-level analysis and visualization.
APID catalogs agile protein interactions and includes a coronavirus interaction dataset.
The Human Protein Atlas organizes protein information across tissues, brain, cells, blood, disease, structure, and interaction resources.
Wiki-Pi supports searching human protein interactions and browsing disease-related interaction networks.
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BioGRID FAQ
What types of interactions does BioGRID index?
It indexes protein and genetic interactions, chemical interactions, and post-translational modifications. The current index lists 3,035,956 protein and genetic interactions, 31,540 chemical interactions, and 1,128,339 post-translational modifications.
Can BioGRID data be downloaded?
Yes. All data are freely provided via the search index and available for download in many standardized formats.
What is BioGRID ORCS?
It is an open repository of CRISPR screens compiled through curation. It is updated quarterly, fully searchable by gene/protein, phenotype, cell line, authors, and other attributes, and all data can be downloaded in standard formats.
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