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PHI-base
PHI-base curates molecular and biological information on genes affecting pathogen-host interactions and some anti-infective targets.
About PHI-base
PHI-base provides curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions, including target sites of some anti-infective chemistries. Content includes pathogens, hosts, diseases, taxonomies, ontologies, and literature citations.
Users can search entries by text with autocomplete, use PHIB-BLAST to find homologs and their phenotypes, download data, view statistics, and submit published phenotype data. A newer interaction-centric version, PHI-base 5, is available, while version 4.19 will remain online until the end of 2027.
Key features
- Text search with autocomplete when entries are found
- PHIB-BLAST to find homologs and their phenotypes
- Download PHI-base data
- View PHI-base statistics
- Submit published phenotype data for curation
- Access developer resources through an API
Best for: Researchers studying genes that affect pathogen-host interactions.
Good for
- Curated data on genes proven to affect pathogen-host interactions
- Includes literature citations, ontologies, and taxonomies
- Provides search, download, statistics, and API access
Watch out for
- Coverage limited to proven genes and some anti-infective chemistry targets
- PHI-base 4 will remain online only until the end of 2027
PHI-base at a glance
- Website
- phi-base.org
- Category
- Research & Data › Open Data & Datasets
- Type
- Website
- Pricing
- Not confirmed. Check the site
- Platforms
- Web
- Open source
- Not stated
- Last checked
- Oct 5, 2026 · Online when checked
- Listed
- Oct 5, 2026
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The Rat Genome Database provides integrated genetic, genomic, physiological, pathway, and disease information with research tools.
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PHI-base FAQ
How should I cite PHI-base?
Urban, M. et al (2025). NAR. doi: 10.1093/nar/gkae1084
Can I submit phenotype data?
Yes, published phenotype data can be submitted for curation.
Will PHI-base 4 remain available?
Yes, PHI-base 4 will remain online until the end of 2027.
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